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Talent Development Careers At Degron Opportunities

Associate Director / Director / Senior Director of DMPK

Location:Shanghai, China     Salary:to be negotiated

Key Responsibilities:

Design and execute in vitro and vivo studies to optimize the pharmacokinetics (PK), pharmacodynamics (PD), absorption, metabolism, distribution, excretion and toxicity (ADMET) for novel therapeutics

Analysis, interpretation, integration, and reporting of DMPK data to characterize PK, efficacy and safety

Collaborate within multidisciplinary project teams to represent DMPK as a subject matter expert

Develop and implement DMPK strategies and project screening funnels that meet program goals by effectively leveraging and managing a global network of CROs

Design and implement fit-for-purpose biomarker strategies in support of a translational plan

Use of modeling and simulation of in vitro and in vivo pharmacokinetic and pharmacodynamic data in support of human dose projections

Develop novel in vivo and in vitro models to solve challenging ADMET and pharmacology issues of drug candidates

Education & Experience Requirements:

Qualified candidates will have a Ph.D. and a minimum of 5-10+ years of relevant industry experience supporting drug discovery programs.

Title/Level can be flexible based on experience.

Must have experience advancing drug discovery programs from target validation to development candidate and beyond.

Experience designing and interpreting PK and PD in vivo studies, and fluency in predicting human PK parameters and efficacious dose-to-man based on nonclinical PK/PD data is required.